Therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products
نویسندگان
چکیده
منابع مشابه
Therapeutic switching: from antidermatophytic essential oils to new leishmanicidal products
This study examined whether the antidermatophytic activity of essential oils (EOs) can be used as an indicator for the discovery of active natural products against Leishmania amazonensis. The aerial parts of seven plants were hydrodistilled. Using broth microdilution techniques, the obtained EOs were tested against three strains of dermatophytes (Trichophyton mentagrophytes, Microsporum gypseum...
متن کاملAntidermatophytic activity of essential oils
The increasing impact of dermatophytic infections, the limitations encountered in their treatments (e.g. resistance, sideeffects, and high toxicity), the rising overprescription and overuse of conventional antifungals and high treatment costs all have stimulated the research for alternative natural drugs, such as essential oils. This paper reviews the in vitro/in vivo activity of essential oils...
متن کاملEvaluation of the Leishmanicidal and Cytotoxic Potential of Essential Oils Derived From Ten Colombian Plants
BACKGROUND The leishmanicidal and cytotoxic activity of ten essential oils obtained from ten plant specimens were evaluated. METHODS Essential oils were obtained by the steam distillation of plant leaves without any prior processing. Cytotoxicity was tested on J774 macrophages and leishmanicidal activity was assessed against four species of Leishmania associated with cutaneous leishmaniasis. ...
متن کاملEssential Oils: From Conventional to Green Extraction
As previously described, EOs are defined as products extracted from natural plants by physical means only such as distillation, cold press and dry distillation. However, the loss of some components and the degradation of some unsaturated compounds by thermal effects or by hydrolysis can be generated by these conventional extraction techniques. These disadvantages have attracted the recent resea...
متن کاملChemical Composition, Leishmanicidal and Cytotoxic Activities of the Essential Oils from Mangifera indica L. var. Rosa and Espada
The essential oils from Mangifera indica var. Rosa and Espada latex were obtained by hydrodistillation and analyzed using GC-FID and GC-MS. Twenty-seven components were identified. The main compound in the essential oil from M. indica var. Espada (EOMiE) was terpinolene (73.6%). The essential oil of M. indica var. Rosa (EOMiR) was characterized by high amounts of β-pinene (40.7%) and terpinolen...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 2015
ISSN: 0074-0276
DOI: 10.1590/0074-02760140332